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Cancer
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Parts of this were taken with permission from Essential Oils Overview and Reference Guide, published by: The Family Tree, 2008

Summary of how oils can help

Please check the Procedures tab for other's experiences using oils.  Also check the Science & Research tab for summaries of important research.  The article below from Johns Hopkins gives great insights into a broad range of considerations in battling cancer.   If you have contributions for this or other health concerns that you would like to share please go to the SUBMIT button on our home page.  Thank you.

Also see Prostate Problems

Also see Chemotherapy

Also see this very interesting article about frankincense from Oman

 

Cancer Update from Johns Hopkins:  After years of telling people chemotherapy is the only way to try to eliminate cancer, Johns Hopkins is finally starting to tell you there is an alternative way.

1. Every person has cancer cells in the body. These cancer cells do not show up in the standard tests until they have multiplied to a few billion. When doctors tell cancer patients that there are no more cancer cells in their bodies after treatment, it just means the tests are unable to detect the cancer cells because they have not reached the detectable size.

2. Cancer cells occur between 6 to more than 10 times in a person's lifetime.

3. When the person's immune system is strong the cancer cells will be destroyed and prevented from multiplying and forming tumors.

4. When a person has cancer it indicates the person has multiple nutritional deficiencies. These could be due to genetic, environmental, food and lifestyle factors.

5. To overcome the multiple nutritional deficiencies, changing diet and including supplements will strengthen the immune system. 

6. Chemotherapy involves poisoning the rapidly-growing cancer cells and also destroys rapidly-growing healthy cells in the bone marrow, gastro-intestinal tract etc, and can cause organ damage, like liver, kidneys, heart, lungs etc.

7. Radiation while destroying cancer cells also burns, scars and damages healthy cells, tissues and organs.

8. Initial treatment with chemotherapy and radiation will often reduce tumor size. However prolonged use of chemotherapy and radiation do not result in more tumor destruction.

9. When the body has too much toxic burden from chemotherapy and radiation the immune system is either compromised or destroyed, hence the person can succumb to various kinds of infections and complications.

10. Chemotherapy and radiation can cause cancer cells to mutate and become resistant and difficult to destroy. Surgery can also cause cancer cells to spread to other sites. 

11. An effective way to battle cancer is to starve the cancer cells by not feeding it with the foods it needs to multiply.

 WHAT CANCER CELLS FEED ON:

       a. Sugar is a cancer-feeder. By cutting off sugar it cuts off one important food supply to the cancer cells. Sugar substitutes like NutraSweet, Equal, Spoonful, etc are made with Aspartame and it is harmful. A better natural substitute would be Manuka honey or molasses but only in very small amounts. Table salt has a chemical added to make it white in colour. Better alternative is Bragg's aminos or sea salt.

       b. Milk causes the body to produce mucus, especially in the gastro-intestinal tract. Cancer feeds on mucus. By cutting off milk and substituting with unsweetened soy milk, cancer cells are being starved.

       c. Cancer cells thrive in an acid environment. A meat-based diet is acidic and it is best to eat fish, and a little chicken rather than beef or pork..  Meat also contains livestock antibiotics, growth hormones and parasites, which are all harmful, especially to people with cancer. 

       d. A diet made of 80% fresh vegetables and juice, whole grains, seeds, nuts and a little fruits help put the body into an alkaline environment.  About 20% can be from cooked food including beans. Fresh vegetable juices provide live enzymes that are easily absorbed and reach down to cellular levels within 15 minutes to nourish and enhance growth of healthy cells. To obtain live enzymes for building healthy cells try and drink fresh vegetable juice (most vegetables including bean sprouts) and eat some raw vegetables 2 or 3 times a day. Enzymes are destroyed at temperatures of 104 degrees F (40 degrees C).

       e. Avoid coffee, tea, and chocolate, which have high caffeine.  Green tea is a better alternative and has cancer-fighting properties.  Water-best to drink purified water, or filtered, to avoid known toxins and heavy metals in tap water. Distilled water is acidic, avoid it.

12.. Meat protein is difficult to digest and requires a lot of digestive enzymes. Undigested meat remaining in the intestines becomes putrefied and leads to more toxic buildup.

13. Cancer cell walls have a tough protein covering. By refraining from or eating less meat it frees more enzymes to attack the protein walls of cancer cells and allows the body's killer cells to destroy the cancer cells.

14. Some supplements build up the immune system (IP6, Flor-ssence, Essiac, anti-oxidants, vitamins, minerals, EFAs etc.) to enable the body's own killer cells to destroy cancer cells. Other supplements like vitamin E are known to cause apoptosis, or programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

15. Cancer is a disease of the mind, body, and spirit. A proactive and positive spirit will help the cancer warrior be a survivor. Anger, unforgiveness and bitterness put the body into a stressful and acidic environment. Learn to have a loving and forgiving spirit. Learn to relax and enjoy life.

16. Cancer cells cannot thrive in an oxygenated environment.  Exercising daily, and deep breathing help to get more oxygen down to the cellular level. Oxygen therapy is another means employed to destroy cancer cells.

Oils & Blends most recommended

Oils Blends Also consider
clove
frankincense
grapefruit
lavender
lemon
sandalwood
thyme
wild orange
AromaTouch
Balance
basil
cypress
marjoram
oregano
peppermint
wintergreen

Procedures (protocols) other folks recommend

Anon - Can someone please tell me what I should recommend to a person that just found out she has breast cancer .  I am overwhelmed with what to suggest for her.  What should she be doing?   So where would you start?  This person knows nothing about oils. Thanks so much.

Pat - Use the cancer protocol that Tamalu (see below) has documented and the doTerra LLW. Teach a member of her family to do the AromaTouch Technique. And follow through with them, making sure they are consistent. Just let her know that she is fighting her cancer with oils that were put here by our creator and He knew what He was doing.

 

                   CANCER PROTOCOL

Tamalu - The following information began with Nicole Stevens, MS.  The original research was her dissertation on therapeutic-grade essential oils and their response in the body to cancer.

We know that chemotherapy is highly toxic and kills healthy cells along with the cancerous cells.  According to the research done by Nicole Stevens, MS, it is not unusual for cancer therapies to kill a large percentage of good cells along with the bad.  This is why we see the signs of hair loss, yellow eyes, grayed hair, nausea, fatigue, etc, from patients on chemotherapy.  According to the research, in a cell count of 100, anything under a healthy cell death rate of 25 is phenomenal. With therapeutic-grade essential oils the cell death count is less than 25 cells.  Nicole Stevens tested repeatedly and has not yet found a toxicity level, even at extremely high concentrations of essential oils. 

Dr. Jaime Matta (Ponce School of Medicine, Ponce, Puerto Rico) found Frankincense to be very effective against even chemotherapy-resistant strains of breast cancer.  The National Institute of Health research shows effectiveness against bladder cancer. Google "frankincense" and "cancer" and as of today you will find 42 papers published.  Watch for more publications of this research. 

There are also other oils which are found to be anti-tumoral; some of them also encourage the re-growth of healthy cells.  Among them are sandalwood, thyme, lavender, and clove.  Understanding the costliness of pure frankincense and sandalwood oils it is exciting to learn that other, less expensive oils may be combined with frankincense and sandalwood and actually increase the effectiveness of a cancer treatment.  Combined with dōTERRA’s Lifelong Wellness Trio, (these are) powerful tools for healing!

NOTE: Frankincense and sandalwood both require much time and care to distill while retaining the proper therapeutic constituents.  For this reason the doTerra products are relatively expensive.  On the other hand, be careful because other sources commonly extract using solvents or shortened distillation to save cost but loose the proper blend of constituents for maximum effectiveness.

This protocol is beginning to be used on a larger scale, by doctors in private practice and in US hospitals at this time.  I was taught to combine it with the Spinal Technique (similar to AromaTouch Technique), daily if possible, and lots of good water to drink.

1)   One 00 capsule Frankincense, One 00 capsule Sandalwood, One 00 capsule Lavender morning and evening for 3 days.  Frankincense, Sandalwood and Lavender topically morning and evening for those same 3 days.

2)   One 00 capsule Frankincense, One 00 capsule Sandalwood, One 00 capsule Wild Orange morning and evening for 3 days.  Frankincense, Sandalwood and Wild Orange topically morning and evening for those same 3 days.

3)   One 00 capsule Frankincense, One 00 capsule Sandalwood, One 00 capsule Lemon… (Repeat process)

4)   One 00 capsule Frankincense, One 00 capsule Sandalwood, One 00 capsule Thyme… (Repeat process)

5)   One 00 capsule Frankincense, One 00 capsule Sandalwood, One 00 capsule Clove… (Repeat process)

The oils may be rotated as often as necessary. 

I am not a doctor, but I do work with doctors whom I trust, and this is what they would do for their family.  I have shared this protocol with family members and friends with tremendous success when the need has arisen. 

Spinal Technique (AromaTouch Technique): Balance and lavender for stress management; melaleuca and OnGuard for immune support; AromaTouch and Deep Blue for inflammatory response; wild orange and peppermint for homeostasis (balancing). Go to the page on AromaTouch Technique for more information.

Pain Formulas

·  White fir and frankincense applied topically. 

*  In a capsule for internal consumption:

*  12 drops wintergreen

*  8 drops vetiver

*  8 drops helichrysum

·  For nerve-type pain, 1/3 00 capsule Vetiver, 1/3 Peppermint, 1/3 Deep Blue topically and internally.

Some may work better for you than others.  The secret with any treatment is finding what works best for your biochemically unique system.

“You will not find concentrations like those in dōTERRA oils anywhere else.”

 

Sunny - Hi, Tamalu!  You are truly an angel!  I have a few more questions, if you don't mind.

My friend, takes Armor Thyroid medication.  Do you think this will conflict with the essential oil cancer protocol?  I told her that it probably would not but IF it did, to cut back on the amount of essential oil drops.  What would you add?

Also sandalwood comes out pretty slow from the bottle.  In fact, I find it challenging to get it to drop out of the bottle.  Do you have any tricks to get it to flow more quickly?

The capsules I know can be bought at any health food store.  When you fill them, don't they dissolve in a short time with the oils in them?   What I'm asking is how long those capsules remain good after they are filled with essential oils?

Tamalu - According to everything I have seen and studied, there will be no conflict with her meds.  I agree, however, that if she is ever uncomfortable or thinks that she sees a problem, she should increase the amount of water she is drinking and decrease (slightly) the amount of essential oils.

Sandalwood is pretty tricky, because it is so thick, but if you remove the reducer from the bottle and insert a hot needle into the vents in the reducer (move the needle around until the vents are enlarged) you can speed it up a LOT.

I know a gal who fills all her capsules a month ahead, but I have heard of others who have had their capsules dissolve.  I generally fill them just as I need them, but it would probably depend on the capsules you're using, what they are made of and such. 

Pat –  The cancer protocol has also been effective for other things including and not limited to renal failure. This is a suggestion only and not a diagnosis or a prescription to treat.

 

Tamera - do you keep repeating the cancer protocol until the cancer is gone? do you do the protocol with chemo and radiation?

Pat - Yes, yes and yes. And one year after you are cancer free you repeat it for another 30 days just to stay on top of those evil cells.

Tamera - Thanks I am nervous to suggest oils to a family member because things don't look good for her. I don't like talking about cost. But if this could save her life I should let them make their choice. I am new to oils but I have seen them bless my life already thanks again.

Kathy - I felt that way in the beginning - but now I have more confidence that these oils can beat cancer and other things that may look terminal or critical.  I have no fear of someday getting cancer because I feel I know first of all how to prevent it and if I get it I feel confident I know how to beat it.

I was told the candida clease, if done regularly, is like a pre cancer protocol.  That is, a great preventative protocol.

Sunny - My friend has started the cancer protocol.  We need a little clarification.  The protocol says to fill the 00 capsules up - one each for frankincense, sandalwood, and the other alternating oils.  I also heard that 3 frankincense and 2 sandalwood bottles would last a little over a month.  My friend has been using a bottle of sandalwood every 3-4 days (26 drops a day).  Did I understand incorrectly about the number of bottles necessary for a month of sandalwood?   Or is it not necessary to fill the entire capsule with sandalwood?

Pat -  I have never been aware of how many bottles the protocol takes, but when my friend was using the protocol they would use 12 to 16 bottles of sandalwood a month. So it does take a lot but if she stays consistent she will notice the benefits. Yes, the capsules are 00 in size and you should fill them.

Samara - Just to ease your mind my dad uses doTerra lavender for his diabetic sores on his legs and to help him sleep.  He has only had wonderful results.  I just found out tonight that my mom started putting lavender and frankincense on some cancer type spots on his ears and they have been going away and/or falling off.  He had a large spot melanoma on his face last year and had to have it surgically removed, so to be able to treat these spots without them getting out of hand is so exciting and comforting for his family.

Editor's note - From tables published by researcher Nicole Stevens (see the Science & Research tab on this page) and using the criteria mentioned the following seems to be the most interesting essential oils for further study.  Shown are those oils found to inhibit a cancer cell line by at least 50%, while not affecting the healthy cells by more than 25%.  (Bold inhibited the cancer cell line by at least 75% and bold/blue by at least 90%)

·  Cervical Cancer:  Douglas fir, frankincense, fir, galbanum, geranium, hyssop, nutmeg, patchouli, ravensara, sage, sandalwood, tarragon, tangerine, tea tree (melalueca), thyme, thyme (linalool), tsuga, valerian, white fir

·  Prostate Cancer: Canadian Red Cedar, dill, myrtle, thyme

·  Breast Cancer: myrtle, sandalwood, tsuga

·  Skin Cancer: grapefruit, hyssop, tarragon, thyme, thyme (linalool)

    The following oils inhibited two or more cancer cell lines: hyssop, myrtle, sandalwood, tarragon, thyme, thyme (linalool), tsuga

Especially for Kids protocols folks recommend for children

 

Everyday Example by Robert James

 

Diet and Nutrition great complements to essential oils

Asparagus & Cancer printed in Cancer News Journal, December 1979. The article presents cases theorizing the discovery of Richard R. Vensal, D.D.S. that asparagus might cure cancer.

Here are a few examples:

Case No. 1, A man with an almost hopeless case of Hodgkin's disease (cancer of the lymph glands) who was completely incapacitated. Within 1 year of starting the asparagus therapy, his doctors were unable to detect any signs of cancer, and he was back on a schedule of strenuous exercise.

Case No. 2, a successful businessman 68 years old who suffered from cancer of the bladder for 16 years. After years of medical treatments, including radiation without improvement, he went on asparagus. Within 3 months, examinations revealed that his bladder tumor had disappeared and that his kidneys were normal.

Case No. 3, a man who had lung cancer. On March 5th 1971, he was put on the operating table where they found lung cancer so widely spread that it was inoperable. The surgeon sewed him up and declared his case hopeless. On April 5th he heard about the asparagus therapy and immediately started taking it.  By August, x-ray pictures revealed that all signs of the cancer had disappeared. He is back at his regular business routine.

Case No. 4, a woman who was troubled for a number of years with skin cancer. She finally developed different skin cancers which were diagnosed by asking specialist as advanced.. Within 3 months after starting on asparagus, her skin specialist said that her skin looked fine and no more skin lesions. This woman reported that the asparagus therapy also cure her kidney disease, which started in 1949. She had over 10 operations for kidney stones, and was receiving government disability payments for an inoperable, terminal, kidney condition. She attributes the cure of this kidney trouble entirely to the asparagus.

I was not surprised at this result, as `The elements of materia medica', edited in 1854 by a Professor at the University of Pennsylvania, stated that asparagus was used as a popular remedy for kidney stones. He even referred to experiments, in 1739, on the power of asparagus in dissolving stones. We would have other case histories but the medical establishment has interfered with our obtaining some of the records. I am therefore appealing to readers to spread this good news and help us to gather a large number of case histories that will overwhelm the medical skeptics about this unbelievably simple and natural remedy.

For the treatment, asparagus should be cooked before using, and therefore canned asparagus is theoretically just as effective, although you want to ensure there are no pesticides or preservatives used. I have corresponded with the two leading canners of asparagus, Giant and Stokely, and I am satisfied that these brands contain no pesticides or preservatives.  I prefer organic, fresh asparagus, wild organic asparagus is even better, but if you have to use canned, it is the next best thing.  

Nutrition of asparagus is best preserved by steam cooking.  This is best done in a double boiler or asparagus cooker. When steaming a bunch you can accommodate for the differences in cooking time by arranging the spears upright and placing them in about two to three inches of water.  You can also add a small amount of quality sea salt. Cover and cook for about five to ten minutes, depending on the size of the spears.  Place the cooked asparagus in a blender with 1-2 drops of quality frankincense essential oil (CPTG) and liquefy to make a puree.  It can be stored in the refrigerator for up to a week..

Give the patient 4 full tablespoons twice daily, morning and evening. Patients usually show some improvement in from 2-4 weeks. It can be diluted with water and used as a cold or hot drink. This suggested dosage is based on present experience, but certainly larger amounts can do no harm and may be needed in some cases. I am convinced of the old saying that `what cures can prevent'. Based on this theory, I have been using asparagus puree as a beverage with our meals. We take 2 tablespoons diluted in water to suit our taste with breakfast and with dinner. I take mine hot and my wife prefers hers cold.

For years we have made it a practice to have blood surveys taken as part of our regular checkups. The last blood survey, taken by a medical doctor who specializes in the nutritional approach to health, showed substantial improvements in all categories over the last one, and we can attribute these improvements to nothing but the asparagus drink. I have made an extensive study of all aspects of cancer, and all of the proposed cures. As a result, I am convinced that asparagus fits in better with the latest theories about cancer.  Asparagus contains a good supply of protein called histones, which are believed to be active in controlling cell growth. For that reason, I believe asparagus can be said to contain a substance that I call cell growth normalizer. That accounts for its action on cancer and in acting as a general body tonic.

In any event, regardless of theory, asparagus used as we suggest, is a harmless substance. The FDA cannot prevent you from using it and it may do you much good.  It has been reported by the US National Cancer Institute, that asparagus is the highest tested food containing glutathione, which is considered one of the body's most potent anticarcinogens and antioxidants.

A note about the “asparagus cancer cure”… There are no peer-reviewed medical studies proving that eating asparagus alone "prevents" or "cures" cancer. That's not to say asparagus offers no cancer-fighting benefits whatsoever — there's a good chance it does, given that it contains vitamin D, folic acid, and the antioxidant glutathione, all thought to play some role in lowering risk factors for certain cancers. By all means, eat your asparagus!

Science and Research what the research is saying

Frankincense and bladder cancer Research Article abstract.  Co-authored by Dr. HK Lin.  This synopsis is taken from www.BioMedCentral.com

Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity

Published: 18 March 2009

Mark Barton Frank1, Qing Yang2 , Jeanette Osban1 , Joseph T Azzarello2,3 , Marcia R Saban3 , Ricardo Saban3 , Richard A Ashley2 , Jan C Welter4 , Kar-Ming Fung5  and Hsueh-Kung Lin2,3,6

1  Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation Microarray Research Facility, Oklahoma City, OK 73104, USA

2  Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

3  Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

4  Department of Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

5  Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

6  Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK 73104, USA

Abstract

Background

Originating from Africa, India, and the Middle East, frankincense oil has been important both socially and economically as an ingredient in incense and perfumes for thousands of years. Frankincense oil is prepared from aromatic hardened gum resins obtained by tapping Boswellia trees. One of the main components of frankincense oil is boswellic acid, a component known to have anti-neoplastic properties. The goal of this study was to evaluate frankincense oil for its anti-tumor activity and signaling pathways in bladder cancer cells.

Methods

Frankincense oil-induced cell viability was investigated in human bladder cancer J82 cells and immortalized normal bladder urothelial UROtsa cells. Temporal regulation of frankincense oil-activated gene expression in bladder cancer cells was identified by microarray and bioinformatics analysis.

Results

Within a range of concentration, frankincense oil suppressed cell viability in bladder transitional carcinoma J82 cells but not in UROtsa cells. Comprehensive gene expression analysis confirmed that frankincense oil activates genes that are responsible for cell cycle arrest, cell growth suppression, and apoptosis in J82 cells. However, frankincense oil-induced cell death in J82 cells did not result in DNA fragmentation, a hallmark of apoptosis.

Conclusion

Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Microarray and bioinformatics analysis proposed multiple pathways that can be activated by frankincense oil to induce bladder cancer cell death. Frankincense oil might represent an alternative intravesical agent for bladder cancer treatment.

 

The following is a synopsis of information presented by Nicole Stevens of Brigham Young University and UNLV Cancer Research Institute.  Her presentation was based on research she had done and was titled, “Natural Synergy, Essential Oils in Cancer Research

Cancer is the second leading cause of death in the United States.  Lung cancer is the most common, followed by breast cancer in women and prostate in men.  One out of every two men and one out of every three women will develop cancer in their lifetime.  This leads to about 1500 deaths each day in the United States costing more that $143 billion annually for medical treatment and early mortality.

Simply stated cancer comes from mutation of cells and the body’s inability to repair DNA mutations.  These mutations come from intracellular problems (DNA copying errors, DNA division errors, and free radicals) as well as extracellular sources (radiation, chemicals, and the environment).

Cancer proves to be difficult to treat for a number of reasons.  Detection is difficult because there is often considerable time between inception and diagnosis complicated by the fact that there are many different types of mutations making them difficult to identify.  Treatments after detection have their problems.  Chemotherapy targets the rapidly proliferating cells typical of cancer cells but may also include good cells such as those in the GI tract, hair , bone marrow, etc. Meanwhile some cancer may not be the rapidly proliferating type.  Radiation is also used but may only kill some of the cancer cells and even further mutate others.  Beyond this each treatment may have the undesirable side effect of compromising the immune system.

Cancer research must look for new treatments.  Plants have a long medicinal history.  Hyssop, spikenard, myrrh and frankincense are all mentioned in the Bible and others have long histories with tribal and other cultural uses. There has been good success so far with plant research as many anti-cancer drugs currently on the market were developed from plants including  Taxol,  Colchicine, and Vincristine.  .  With only about 1% of the higher plants being exhaustively studied there is a very high probability that new drugs remain to be found. 

Plant extractions (essential oils) contain many physiologically active chemical constituents (i.e. terpenoids, phenols, and coumarins) making them of interest for research.  They have the proven capability (individually or in combinations) to have beneficial properties:

·  Protective: coping with environmental stress

·  Destructive: killing or inhibiting growth of invaders

·  Stimulatory: promoting cell growth

Ms. Stevens’ initial research screened 69 essential oils and 5 blends, testing them against cervical, breast, skin and prostate cancer cell lines as well as non-cancerous 3T3 (mouse) fibroblast cells.  Her criterion was to recommend for further study as potential anticancer drugs any oilils showing 50% or more cancer cell inhibition and 25% or less inhibition of non-cancerous cell.  Also of note were any correlations between which oils are active against which cancer cell lines.

These results noted were:

��  58% of the 74 oils showed general cancer inhibition of 50% or greater

·  34% of the 74 oils showed cancer-specific inhibition

·  Seven of these were active against two or more cancer cell lines

Ms. Stevens noted these conclusions:

·  Essential oils have potential as anticancer drugs

·  Screening processes (such as the one used in this study) that are fast, inexpensive and useful provide good leads about which compounds should be further investigated

·  Further research should be done on promising essential oils—this may lead to new cancer drugs

·  Areas of interest

*   Stimulating apoptosis  

*  DNA repair  

*  Proliferative senescence  

*  Immune protection and stimulation  

*  Preventing metastasis

Editor's note - From the tables published by Ms. Stevens and the criteria mentioned the following seems to be the most interesting essential oils for further study.  Shown are those oils found to inhibit a cancer cell line by at least 50%, while not affecting the healthy cells by more than 25%.  (Bold inhibited the cancer cell line by at least 75% and bold/blue by at least 90%)

·  Cervical Cancer:  Douglas fir, frankincense, fir, galbanum, geranium, hyssop, nutmeg, patchouli, ravensara, sage, sandalwood, tarragon, tangerine, tea tree (melalueca), thyme, thyme (linalool), tsuga, valerian, white fir

·  Prostate Cancer: Canadian Red Cedar, dill, myrtle, thyme

·  Breast Cancer: myrtle, sandalwood, tsuga

·  Skin Cancer: grapefruit, hyssop, tarragon, thyme, thyme (linalool)

    The following oils inhibited two or more cancer cell lines: hyssop, myrtle, sandalwood, tarragon, thyme, thyme (linalool), tsuga

 

The following sources were noted:

• American Cancer Society. 2004. Cancer Facts and Figures.

• Baladrin, M.F., A.D. Kinghorn, and N.R. Farnsworth. 1993. Plant-derived natural products in drug discovery and development. In: Human Medicinal Agents from Plants (ACS symposium 1992). A.D. Kinghorn and M.F.Balandrin, eds. American Chemical Society: 2-12.

• Balick, M.J., and P.A. Cox. 1996. Plants, People and Culture: The Science of Ethnobotany. Scientific American Library, New York.

• Beuchat, L.R. 1994. Antimicrobial properties of spices and their essential oils. Nat. Antimicrob. Syst. Food Preserv. 167-79.

• Cragg, G.M., D.J. Newman and K.M. Snader. 1997. Natural products in drug discovery and development. Journal of Natural Products 60: 52-60.

• Deans, S.G., and G. Ritchie. 1987. Antibacterial properties of plant essential oils. International Journal of Food Microbiology 5: 165-180.

• Hostettmann, K., A. Marston, and J.L. Wolfender. 1995. Strategy in the search for new biologically active plant constituents. In: Phytochemistry of Plants Used in Traditional Medicine. Clarendon Press, Oxford: 17-45.

• Johnson, T. 1999. CRC Ethnobotany Desk Reference. CRC Press, Boca Raton.

• Kuo, Y.H., and M.L. King. 2001. Antitumor drugs from the secondary metabolites of higher plants. In: Bioactive Compounds from Natural Sources. Corrado Tringali, ed. Taylor and Francis, London: 191-269.

• Maruzzella, J.C., and N.A. Sicurella. Antibacterial activity of essential oil vapors. Journal of the American Pharmaceutical Association 49(11): 692-695.

• Powis, G. 1991. Toxicity of anticancer drugs to humans: a unique opportunity to study human toxicology. In The Toxicity of Anticancer Drugs. G. Powis and M.P. Hacker, eds. Pergamon Press, New York: 1-9.

• Suffness, M., and J.M. Pezzuto. 1991. Assays related to cancer drug discovery. In: Methods in Plant Biochemistry, Vol. 6: Assays for Bioactivity. P.M. Dey, J.B. Harbourne, and K. Hostettmann, eds. Academic Press, London: 71-133.

• Teranishi, K., and S. Kint. 1993. Bioactive volatile compounds from plants. In: Bioactive Volatile Compounds from Plants. R. Teranishi, R.G. Buttery, H. Sugisawa, eds. American Chemical Society, Washington D.C.: 1-5.

• Vlietnick, A.J., and S. Apers. 2001. Biological screening methods in the search for pharmacologically active natural products. In: Bioactiv e Compounds from Natural Sources. Corrado Tringali, ed. Taylor and Francis, London: 1-29.

• http://www.youngliving.us

• http://www.essentialoils.co.za/components.htm. “The chemistry of essential oils, and their chemical components.”

 

Research Report on Frankincense and Breast Cancer co-authored by Jaime Matta PhD.

41st ACS Junior Technical Meeting & 26th Puerto Rico Interdisciplinary Scientific Meeting (PRISM), University of Puerto Rico at Cayey

Santos Colón, Karla Marie, UNIV. CATOLICA; Ruiz Abigail, Pharmacology, Physiology and Toxicology Ponce School of Medicine; Matta Jaime Ph.D., Pharmacology, Physiology and Toxicology Ponce School of Medicine

The Induction of Apoptosis in (MCF-7) Human Breast Cancer Cell Line by Frankincense Essential Oil

Breast cancer (BC) is the most common type of cancer among women in the United States and in Puerto Rico. It is the leading cause of cancer deaths among young women. Despite significant advances in BC diagnosis and treatment, resistance to chemotherapeutic drugs is one of the most important challenges in the treatment of this disease. The MCF-7 cell line is a model for an aggressive human BC that is highly resistant to chemotherapy. Frankincense essential oil (FEO) is an essential oil distilled from Boswellia carteri and B. serrata. It contains at least 70 compounds including limonene, sabinene, monoterpenes and pentacyclic triterpenes. The compounds present in FEO can synergistically suppress the proliferation and apoptosis of different tumor types. Boswellic acids present in FEO have been identified as a pharmacologically active compounds which inhibit leukotriene biosynthesis, 5- lipoxygenase and exert antiproliferative activity. Prevention, inhibition, and regression of various cancer types have been induced by chemicals component of FEO. Previous studies in our laboratory showed that FEO at doses ranging from 80 to 180 μg/ml decreases up to 94% the cell viability of MCF-7 cells. The purpose of this study was to determine if apoptosis (programmed cell death) is one of the mechanisms associated with this decrease in cell viability induced by FEO. Previous studies established IC50 of around 100μg/ml a dose in which grow of a drug resistant cell line is inhibited. The MCF-7 cells were treated with the established IC50 for 24 hours. Apoptotic and necrotic cells were respectively detected with annexin V and propidium iodide. This study will determine if FEO has chemotherapeutical properties in vitro against MCF-7 BC cells.

 

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